I'm surprised Ridley Scott isn't directing the pilot! But I guess he's got his hands full with Napoleon. Villeneuve probably won't direct because he's got all the Dune stuff going on, with Part Two in post-production and The Sisterhood (which he's exec. producing and directing the pilot) still happening.
https://variety.com/2023/tv/news/blade-runner-2099-jeremy-podeswa-amazon-1235554075/
