In 2029, Aahna "Ash" Ashina has returned to her career as a Blade Runner, but instead of retiring replicants, she secretly helps them escape. After the Los Angeles Police Department receives an anonymous tip about replicants working on construction of the Sepulveda Sea Wall, Ash is assigned to investigate.
Ash reaches the construction site and sees a replicant, who immediately runs from her. When she catches up to him, the replicant says "Yotun redeems" before jumping to his death. Sensing a familiarity in the name Yotun, Ash conducts research, finding records of a replicant who managed to overpower her and escape in 2017.
Ash examines the body of the replicant she chased, but her colleague Pearl suspects he was human, due to the lack of a serial number in his eye. Ash's leads in the case lead her nowhere and she makes her way to The Diamant, a secret club for replicants. There, she asks the bartender if she knows anything about the name Yotun, which piques the interest of Lelia, a woman sitting at the bar. The woman leaves and Ash follows her.
Ash tracks Lelia down to a cab, but she throws one of the doors off at Ash, allowing her to slip away. Freysa, not far behind, comes to Ash's aid and notices that Lelia dropped her purse. An address inside the purse leads Ash and Freysa to a high-rise. Inside, they find a multitude of glass tanks containing replicants.
Yotun and Kalia observe tanks containing replicants, reflecting upon Eldon Tyrell's flawed legacy, noting that while Tyrell profited from creating life, Yotun restores life to redeem it. Yotun grows weary, so Kalia suggests a rejuvenation.
Ash returns to the LAPD precinct, where she learns about the death of Ruskin, a Blade Runner. Ruskin, who was in the middle of an investigation into the murder of Hyman Bask, was found dead in his apartment with his spine torn out by hand. Believing Ruskin's murder to have the same perpetrator as Bask's, Ash's captain puts her on the Bask case. She begins this investigation at Ruskin's house, finding his files on the case, learning of the missing servant Ducasse.
At a ceremony, Yotun requests a sacrifice of life by one of his followers, in order to further extend his own. Yotun readily provides Yotun with some of his own life. Afterward, Lelia approaches Yotun to tell him that she has found Ash. Yotun asks her to find Ash again.
Returning home, Ash finds Lelia waiting for her. Lelia asks Ash to accompany her to Yotun, but Ash refuses, instead asking for Yotun's location. Due to Ash's refusal, Lelia attacks her, knocking her out and taking her outside to a spinner, taking off just as Freysa is arriving home.
Yotun and his entourage go to an airship where a party attended by Los Angeles' elite takes place. Incapacitating the front security, the group gains entry by using Bask's eyeball.
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