Off-world: The Blade Runner Wiki
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Jeter Continuity

The St. Paul incident occurred when a Los Angeles Police Department Blade Runner traveled to St. Paul, Minnesota to celebrate Christmas with his family.

After becoming intoxicated, he jokingly subjected his high school girlfriend to the Voigt-Kampff test, but she failed due to being under the influence of an upper-respiratory humectant, which altered her iris fluctuations and blush response. Believing that she failed because she was a replicant, the Blade Runner killed her.[1]

He then subjected his family – who were also on the drug – to the test and killed them. Another LAPD Blade Runner was sent to execute the vacationing officer, whose body was flown back to Los Angeles and buried with honors, while the police stayed quiet on the matter.[1]